A risk calculator to predict suicide attempts among individuals with early-onset bipolar disorder.

ABSTRACT:

Objectives

To build a one-year risk calculator (RC) to predict individualized risk for suicide attempt in early-onset bipolar disorder.

Methods

Youth numbering 394 with bipolar disorder who completed ≥2 follow-up assessments (median follow-up length = 13.1 years) in the longitudinal Course and Outcome of Bipolar Youth (COBY) study were included. Suicide attempt over follow-up was assessed via the A-LIFE Self-Injurious/Suicidal Behavior scale. Predictors from the literature on suicidal behavior in bipolar disorder that are readily assessed in clinical practice were selected and trichotomized as appropriate (presence past 6 months/lifetime history only/no lifetime history). The RC was trained via boosted multinomial classification trees; predictions were calibrated via Platt s

SUBMITTER: Goldstein TR 

PROVIDER: S-EPMC12532099 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature