Salicylic acid inhibits V-ATPase activity and restricts cell elongation.

ABSTRACT: While the role of salicylic acid (SA) in plant defence has been investigated for decades, its role in regulating plant growth and development has only come into focus recently. SA application inhibits growth independently of the established "Nonexpressor of Pathogenesis Related" (NPR) receptors. However, the underlying mechanism at the cellular level remains largely elusive. Here, we show that SA induces changes in vacuolar morphology and a significant increase in vacuolar pH in Arabidopsis (Arabidopsis thaliana). We demonstrate SA-mediated inhibition of V-ATPase activity, which is confirmed by experiments using the V-ATPase mutant vha-a2 vha-a3. The observed effects seem to be independent of the phytohormone auxin, which has been reported to crosstalk with SA. By inhibiting V-ATPase activ

SUBMITTER: Muller J 

PROVIDER: S-EPMC12532109 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature