Effect of erector spinae plane block on overall benefit of analgesia after esophagectomy: a randomized controlled trial protocol.

ABSTRACT:

Introduction

Management of postoperative pain following esophagectomy is challenging. This study aims to investigate the analgesic efficacy and overall clinical benefit of erector spinae plane block (ESPB) using either liposomal bupivacaine or ropivacaine in patients undergoing esophagectomy.

Patients and methods

This single-center, randomized, double-blind, placebo-controlled trial will be conducted at the First Affiliated Hospital of Soochow University. Eighty-four adult patients scheduled for transthoracic esophagectomy will be randomized (1:1:1) to receive a preoperative ultrasound-guided ESPB using either liposomal bupivacaine, ropivacaine, or normal saline placebo. All patients will receive standardized general anesthesia and postoperative patient-controlled intravenou

SUBMITTER: Chong YZ 

PROVIDER: S-EPMC12532356 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature