Development and validation of a novel nomogram incorporating psychosocial factors for predicting hypoglycemia during perioperative period of digestive endoscopy (DREAM-Hypo Model).

ABSTRACT:

Background

Perioperative hypoglycemia during digestive endoscopy poses significant risks, with reported incidence rates of 6.75-18.70%. Traditional models focus on metabolic factors, while psychosocial stressors (anxiety, poor sleep quality) may exacerbate risk through neuroendocrine dysregulation. This study aims to develop a novel nomogram (DREAM-Hypo Model) integrating psychosocial, clinical, and metabolic predictors for hypoglycemia risk stratification.

Methods

We prospectively enrolled 610 patients undergoing therapeutic digestive endoscopy at The First Affiliated Hospital of Ningbo University, China (Jan-Jun 2024). Participants were randomly allocated to training and validation cohorts (7:3 ratio). Predictors were identified via univariate and multivariate logistic reg

SUBMITTER: He X 

PROVIDER: S-EPMC12532470 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature