Indocyanine green (ICG) fluorescence guided lymph node mapping for determination of resection margins in colon cancer - ISCAPE trial.

ABSTRACT:

Background

Indocyanine green (ICG) lymphangiography for colon cancer has been regarded as a sentinel lymph node (LN) detection tool, but its repeatedly reported suboptimal sensitivity rates suggest that approach aiming to define locoregional lymphatic collector margins might be more efficient in guiding surgeon's decision making. Thus, present study was designed to determine if sensitivity of the latter approach is sufficient to guide resection margins' selection in colon cancer surgery.

Methods

This is a prospective, single-centre, single-arm phase II interventional trial, including patients with histologically confirmed colon adenocarcinoma. ICG was injected subserosally in the beginning of operation, fluorescence was assessed 30 min after injection or later, when it becam

SUBMITTER: Panaiotti L 

PROVIDER: S-EPMC12532654 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature