The additive effect of glycemic variability and systolic blood pressure variability on mortality in patients with sepsis.

ABSTRACT:

Objective

Glycemic variability (GV) and systolic blood pressure variability (SBPV) have been reported to be associated with all-cause mortality. However, it remains unclear whether the combination of these parameters further stratifies mortality risk in septic patients admitted to the intensive care unit (ICU). The aim of this study was to investigate the combined association of GV and SBPV with mortality in patients with sepsis.

Methods

The study utilized data from MIMIC-IV database. Patients with sepsis were stratified into four groups. The endpoint indicators of this study include ICU mortality, in-hospital mortality, 30-day mortality, 90-day mortality, 180-day mortality, and 1-year mortality. Kaplan-Meier method was used to estimate the survival curves. The risks of ICU

SUBMITTER: Zhang HJ 

PROVIDER: S-EPMC12532877 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature