The link of carbon catabolite repression elements, small RNAs CrcY and CrcZ and polyhydroxyalkanoate metabolism in Pseudomonas putida KT2440.

ABSTRACT:

Background

Polyhydroxyalkanoates (PHAs), biodegradable polymers, can be synthesised and degraded by a number of bacteria. With a range of monomer composition and molecular weight, these polymers can be used for packaging to medical applications. However, the production cost, inadequate mechanical properties, and challenging melt processing properties are major impediments. Understanding and harnessing the regulatory networks underpinning PHA production in a model organism Pseudomonas putida KT2440 is an invaluable tool to increase PHA production and alter polymer properties for specific applications.

Results

The small RNAs CrcY and CrcZ, key components of the carbon catabolite repression (CCR) system, are implicated in PHA metabolism in P. putida KT2440. Their in trans overe

SUBMITTER: Che Y 

PROVIDER: S-EPMC12533007 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature