Prediction model for extrathyroidal extension in thyroid papillary carcinoma based on ultrasound radiomics.

ABSTRACT: This study aimed to construct preoperative prediction models for extrathyroidal extension (ETE) in papillary thyroid carcinoma (PTC) based on ultrasonic radiomics and explore their clinical application value. This retrospective study included PTC patients treated across three centers from 2015 to 2023. Data for 609 cases from two centers were utilized for model construction and divided 4:1 into a training set (n = 487; 144 with ETE and 343 without ETE) and test set (n = 122; 58 with ETE and 64 without ETE). The external validation set comprised 109 PTC patients from the third center (n = 109; 55 with ETE and 54 without ETE). Image features were extracted using Pyradiomics. Feature selection and dimensionality reduction were performed using the least absolute shrinkage and selection operato

SUBMITTER: Yuan SS 

PROVIDER: S-EPMC12533030 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature