Computational analysis of L4-L5 interspinous process devices and interbody fusion spacers using ceramic and polymeric materials via finite element modeling and artificial intelligence.
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ABSTRACT: Lumbar spinal stenosis involves pathological narrowing of the spinal canal, whereas disc degeneration refers to the progressive deterioration of intervertebral disc structure and function. Interspinous process devices (ISPs) are commonly used to manage spinal stenosis, whereas anterior lumbar interbody fusion (ALIF) spacers are employed for conditions such as spondylolisthesis and disc degeneration. Although titanium remains the standard material for spinal devices, ceramics and polymers have emerged as promising alternatives because of their favorable biomechanical and biological properties. This study investigated the biomechanical performance of ceramic- and polymer-based materials in ALIF and ISP devices via finite element method (FEM) simulations and further explored the potential of
SUBMITTER: Shash YH
PROVIDER: S-EPMC12533109 | biostudies-literature | 2025 Oct
REPOSITORIES: biostudies-literature
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