Associations between depression and risk of cardiometabolic multimorbidity among middle-aged and older Chinese adults.

ABSTRACT: Numerous studies have performed the association between depression and increased risk of cardiometabolic diseases (CMDs). However, there is limited understanding regarding the impact of the depression on cardiometabolic multimorbidity (CMM), particularly the various combinations of CMM. The purpose of this study was to explore the association between depression and CMM. We followed 9746 adults in the China Health and Retirement Longitudinal Study from 2012 to 2020. CMM was defined as the coexistence of ≥ 2 CMDs, including diabetes, heart disease, and stroke. Depression was assessed by the scale of the Center for Epidemiologic Studies Depression Scale-10 (CESD-10). We used Cox proportional hazards regression models and restricted cubic spline regression models to examine associations betwee

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC12533173 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature