Directed Self-Assembly of Magnetic Bioceramic Deep Inside Dentinal Tubules May Alleviate Dental Hypersensitivity.

ABSTRACT: Delivery of regenerative medicine in complex, microscale topographies can revolutionize multiple areas of healthcare, including but not limited to orthopaedics and dentistry. The technical challenges include navigation and regeneration of nanoscale biosimilars with spatial control, necessitating a different technological approach, as demonstrated here. The specific problem addressed here is dental hypersensitivity, which occurs when dentinal tubules are exposed to the external environment through enamel loss or cementum erosion of the tooth, thus stimulating nerves located in the peripheral odontoblast zone of the pulp. Existing treatments, such as sensitive toothpaste and adhesive resins, are limited to the surface and can only provide short-term relief. Here, we deploy a confluence of di

SUBMITTER: Peddi S 

PROVIDER: S-EPMC12533301 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature