What does taking olanzapine mean to young people with anorexia nervosa and their families? Findings from the OPEN feasibility trial.

ABSTRACT:

Background

Olanzapine is a second-generation antipsychotic medication often prescribed for young people with Anorexia Nervosa (AN), though supporting evidence is limited. The OPEN feasibility trial of olanzapine for young people (12-24 years) with AN, explored the feasibility of a future definitive trial on olanzapine in young people. Qualitative interviews examined the acceptability of olanzapine and trial design among young people with AN and their families. Here, we explore: what does taking olanzapine mean to young people with AN and their families, specifically regarding decisions to take or decline it?

Methods

Twelve young people who agreed to take olanzapine, two who declined, and four parents took part in semi-structured qualitative interviews, which were conducted a

SUBMITTER: Olive RR 

PROVIDER: S-EPMC12533353 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature