Association of Remnant Cholesterol with Platelet Reactivity in Coronary Artery Disease Patients Receiving PCI.

ABSTRACT:

Background

Remnant cholesterol (RC) has received increasing attention and shown to be associated with bleeding and ischemic events in clinical research; however, the mechanisms remain incompletely understood.

Aim

To investigate the relationship between RC and platelet reactivity in patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) who received dual antiplatelet therapy with aspirin and clopidogrel.

Methods

A total of 10,724 consecutive PCI patients in China from January 2013 to December 2013 were enrolled. 6,633 patients had the results of thromborlastogram for analysis. Low on-treatment platelet reactivity (LTPR) and high on-treatment platelet reactivity (HTPR) were defined as adenosine diphosphate-induced platelet maximu

SUBMITTER: Liu M 

PROVIDER: S-EPMC12533439 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature