Association between triglyceride-glucose index and postoperative delirium following cardiac surgery: a multicenter retrospective analysis.

ABSTRACT:

Background

Postoperative delirium (POD) after cardiac surgery correlates with adverse outcomes, increasing healthcare burdens and hindering patient recovery.The triglyceride-glucose (TyG) index, a marker of insulin resistance, shows cardiovascular prognostic value.This study sought to explore the association between the TyG index and the development of POD in patients undergoing cardiac surgery.

Methods

This multicenter retrospective cohort study included 1,850 patients (MIMIC-IV: n = 1,461; Yuhuangding: n = 389). A four-knot restricted cubic spline (RCS) regression analyzed the nonlinear relationship to determine the TyG threshold. Multivariable logistic regression and propensity score matching (PSM) controlled for baseline differences.Subgroup analyses were conducted.

R

SUBMITTER: Zeng J 

PROVIDER: S-EPMC12533457 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature