Development and Validation of an Incident Hypertension Risk Prediction Model for Young Adults.

ABSTRACT:

Background

Identifying young adults at high risk of hypertension can improve blood pressure screening recommendations.

Methods

We developed models to predict incident hypertension using diverse contemporary cohorts of young adults aged 18 to 39 years from Kaiser Permanente Southern California (derivation and internal validation) and 3 cohort studies (CARDIA [Coronary Artery Risk Development in Young Adults], FHS [Framingham Heart Study], HCHS/SOL [Hispanic Community Health Study/Study of Latinos]; external validation). Predictors included age, systolic and diastolic blood pressure, body mass index, smoking, social determinants of health, comorbidities, high- and low-density lipoprotein cholesterol, and pregnancy-related hypertensive disorders. We used Cox elastic net and ran

SUBMITTER: An J 

PROVIDER: S-EPMC12533609 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature