Effects of Alcohol Septal Ablation on Exercise Hemodynamics, Symptoms, and Quality of Life in Obstructive Hypertrophic Cardiomyopathy.

ABSTRACT:

Background

The impact of alcohol septal ablation (ASA) on exercise hemodynamics, symptoms, and quality of life in patients with obstructive hypertrophic cardiomyopathy is poorly described according to contemporary standards. This study aimed to evaluate the effect of ASA on filling pressures at rest and during exercise, left ventricular outflow tract obstruction, symptoms, and quality of life in patients with obstructive hypertrophic cardiomyopathy.

Methods

This prospective study enrolled 24 patients with obstructive hypertrophic cardiomyopathy referred for ASA. Right-heart catheterization and echocardiography were performed at rest and during exercise, before and ≈7 months after ASA. The primary outcome was the difference in pulmonary artery wedge pressure at 75 W. Secondar

SUBMITTER: Dybro AM 

PROVIDER: S-EPMC12533624 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature