Age-Specific Association Between Cumulative Blood Pressure Exposure and Atrial Fibrillation Risk in Adults.

ABSTRACT:

Background

The association between cumulative blood pressure (BP) exposure and atrial fibrillation (AF) risk across different age groups remains unclear.

Methods

We analyzed 77 180 participants from the Kailuan Study who were free of AF and had complete BP data from 2006 to 2010. Time-weighted average BP was calculated as the sum of each interval's mean BP multiplied by the corresponding time interval, divided by total exposure duration. Participants were divided into 4 groups by time-weighted average BP quartile: quartiles 1 (reference), 2, 3, and 4.

Results

Among 77 180 participants, 57 344 were young and middle-aged adults (aged <60 years), and 19 836 were older adults (aged ≥60 years). During a median follow-up of 12 years, 746 (0.97%) participants developed AF, i

SUBMITTER: Yan Y 

PROVIDER: S-EPMC12533625 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature