Left Atrial Remodeling Identification and Catheter Ablation Outcomes With ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography in Persistent Atrial Fibrillation.

ABSTRACT:

Background

Left atrial structural remodeling contributes to the persistence of atrial fibrillation (AF) and influences the outcomes of catheter ablation (CA). We investigated the usefulness of ¹⁸F-fluorodeoxyglucose-positron emission tomography in detecting low atrial glucose uptake (LGU) as a potential marker of fibrosis and its predictive value for CA success in persistent AF.

Methods

Thirty-six patients without diabetes with persistent AF scheduled for CA underwent nicotinic acid-stimulated ¹⁸F-fluorodeoxyglucose-positron emission tomography to assess global and segmental LGU before CA. LGU was compared with low voltage areas on electroanatomical mapping, left atrial volume index via echocardiography, and late gadolinium enhancement from cardiac magn

SUBMITTER: Raoult T 

PROVIDER: S-EPMC12533631 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature