Long-Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study.

ABSTRACT:

Background

The association between transient ischemic attack (TIA) and dementia is incompletely characterized. Determining the cognitive sequalae of TIA is important as it can function as an early warning sign or additional risk factor for dementia. We sought to determine the long-term incidence of post-TIA dementia and examined whether TIA prompts changes in vascular risk factors.

Methods

Nested matched longitudinal cohort study within the community-based Framingham Heart Study. A prospectively collected sample of participants without dementia or transient ischemic attack were matched on age and sex (5:1) to participants with first incident TIA >60 years. The primary outcome of interest was the 20-year incidence of all-cause dementia.

Results

The study matched 297 pa

SUBMITTER: Lioutas VA 

PROVIDER: S-EPMC12533647 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature