Atrial Natriuretic Peptide at Discharge as a Predictive Marker for Early Rehospitalization in Patients With Heart Failure With Preserved Ejection Fraction.

ABSTRACT:

Background

Patients admitted for heart failure with preserved ejection fraction (HFpEF) are at risk for rehospitalization, especially within 90 days post discharge. NPs (natriuretic peptides), namely ANP (atrial NP) and BNP (brain NP), are important biomarkers in HF management, but their role in predicting early rehospitalization in patients with HFpEF remains unclear.

Methods

A retrospective analysis was conducted on 147 patients with HFpEF hospitalized for HF. ANP and BNP levels were measured at admission and discharge. Rehospitalization events were analyzed to evaluate the prognostic impact of NPs.

Results

Among 147 patients, 47 (32.0%) were rehospitalized within 1 year, including 22 (15.0%) within the 90 days postdischarge. Elevated discharge ANP (>113 pg/mL) was

SUBMITTER: Ohno J 

PROVIDER: S-EPMC12533653 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature