Early Cardiac Dysfunction in Adolescents With Low Vigorous Physical Activity.

ABSTRACT:

Background

Adverse left ventricular diastolic function (LVDF) is an early marker of cardiac dysfunction that worsens with age and can lead to heart failure. It is unclear when this deterioration begins and whether physical activity (PA) influences it. We assessed the independent relationships of adverse LVDF in adolescents with different PA intensities, compared to the association with adiposity. The impact of adverse LVDF from low PA on cardiorespiratory fitness was examined.

Methods

In 127 adolescents (aged 11-18 years), we assessed LVDF by echocardiography, 7-day PA by wrist-worn accelerometry, adiposity Z scores by bioimpedance, and peak oxygen consumption by cardiopulmonary exercise testing (OxSOCRATES [Oxfordshire Sedentariness, Obesity, and Cardiometabolic Risk

SUBMITTER: Burden SJ 

PROVIDER: S-EPMC12533748 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature