Dosimetric comparison of Monte Carlo, Acuros XB, and anisotropic analytical algorithm for lung cancer plans on halcyon accelerators.

ABSTRACT: This study evaluates the differences in application of the RayStation Monte Carlo algorithm (RMC) compared to Acuros XB (AXB) and the Anisotropic Analytical Algorithm (AAA) in Eclipse for conventional radiotherapy planning of lung cancer using the novel ring-shaped Halcyon accelerator. A total of 63 non-small-cell lung cancer patients were retrospectively included, with a prescription dose of 60 Gy delivered in 30 fractions. Radiotherapy plans were initially designed and optimized in RayStation, then recalculated in Eclipse using AXB and AAA to assess algorithmic differences in dose distributions. Analysis of data from 63 patients, combined with simulations using square fields and cylindrical water phantoms, revealed that RMC and AXB achieved high consistency in target dose coverage and co

SUBMITTER: Shao K 

PROVIDER: S-EPMC12533868 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature