Frontal and parietal planning signals encode adapted motor commands when learning to control a brain-computer interface.

ABSTRACT: Perturbing visual feedback is a powerful tool for studying visuomotor adaptation. However, unperturbed proprioceptive signals in common paradigms inherently co-varies with physical movements and causes incongruency with the visual input. This can create challenges when interpreting underlying neurophysiological mechanisms. We employed a brain-computer interface (BCI) in rhesus monkeys to investigate spatial encoding in frontal and parietal areas during a 3D visuomotor rotation task where only visual feedback was movement-contingent. We found that both brain regions better reflected the adapted motor commands than the perturbed visual feedback during movement preparation and execution. This adaptive response was observed in both local and remote neurons, even when they did not directly cont

SUBMITTER: Ferrea E 

PROVIDER: S-EPMC12533969 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature