SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in <i>Streptococcus pneumoniae</i>.

ABSTRACT: The unprecedented number of Streptococcus pneumoniae (the pneumococcus) genomes sequenced in recent years has accelerated the discovery of novel serotypes and highlighted the genetic diversity both between and within each serotype. A novel serotype should demonstrate a distinct cps locus, capsular structure and serological profile. In only the past 4 years, nine new serotypes have been identified. Accurate and timely serotyping of pneumococcal isolates is key to understanding their global distribution, evolution and the response of the bacterial population to vaccination. However, current bioinformatics serotyping tools are infrequently updated and struggle to accommodate the rapid discovery of new serotypes in a timely manner. To address these limitations, we built a compreh

SUBMITTER: Lorenz O 

PROVIDER: S-EPMC12534171 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature