Incidence and Predictors of Ocular Complications in Pediatric-Onset Uveitis: Data from the AIDA Network Uveitis Registry.

ABSTRACT:

Introduction

This study aims to describe complications of pediatric-onset uveitis and their predictors among baseline and treatment-related factors.

Methods

This registry-based observational study included patients with noninfectious uveitis with disease onset < 18 years.

Results

A total of 309 patients were enrolled (535 eyes). Uveitis was anterior in 290 eyes (54.2%), panuveitis in 121 (22.6%), intermediate in 88 (16.4%), and posterior in 24 (4.5%). Over a median follow-up of 49.0 months (interquartile range [IQR] 101.0), 137 children (44.3%) developed ≥ 1 complication (14.4 per 100 patient-years). Idiopathic uveitis (p < 0.001), longer topical glucocorticoid (GC) monotherapy (p < 0.001) and longer delay of immunosuppressive therapy (IST) (p = 0.03) were associated

SUBMITTER: Gaggiano C 

PROVIDER: S-EPMC12534201 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature