Ethnic diversity in precision medicine: a reality or an aspiration?

ABSTRACT: Precision medicine seeks to tailor prevention, diagnosis and treatment strategies to the biological and contextual characteristics of individuals. In diabetes, where there is substantial heterogeneity in risk, progression and treatment response, this approach holds particular promise. However, the majority of precision medicine research has been conducted in populations of White European ancestry, limiting its relevance and equity across ethnically diverse groups. This review examines the role of ethnicity in precision diabetes medicine, highlighting its potential value and limitations. It summarises evidence for ethnic variation in both type 1 and type 2 diabetes, including differences in susceptibility, phenotypes and complications, and demonstrates how under-representation in research h

SUBMITTER: Misra S 

PROVIDER: S-EPMC12534348 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature