Modulation of brain oscillations by continuous theta burst stimulation in patients with insomnia.

ABSTRACT: Continuous theta burst stimulation (cTBS) induces long-lasting depression of cortical excitability in motor cortex. In the present study, we explored the modulation of cTBS on resting state electroencephalogram (rsEEG) during wakefulness and subsequent sleep in patients with insomnia disorder. Forty-one patients with insomnia received three sessions active and sham cTBS in a counterbalanced crossover design. Each session comprised 600 pulses over right dorsolateral prefrontal cortex. Closed-eyes rsEEG were recorded at before and after each session. Effects of cTBS in subsequent sleep were measured by overnight polysomnography screening. Power spectral density (PSD) and phase locking value (PLV) were used to calculate changes in spectral power and phase synchronization after cTBS during wak

SUBMITTER: Zhu X 

PROVIDER: S-EPMC12534500 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature