Associations between perceived excessive maternal control in childhood, well-being, and dorsal striatum volume in older adults.

ABSTRACT: Maternal bonding has been linked to the functioning of the dorsal striatum. Our aim was to examine how midlife perceptions of maternal parenting relate to late-life brain volume using the "Insight 46" neuroimaging sub-study of the MRC National Survey of Health and Development (NSHD) 1946 birth cohort. In a cross-sectional design, we investigated associations between retrospective maternal bonding and dorsal striatal volumes (bilateral caudate and putamen) in 452 cognitively healthy older adults with similar socio-economic backgrounds. Maternal care, control, and autonomy up to age 16 were reported at age 43, and T1-weighted brain images were acquired at age 70. K-means clustering categorized participants into three groups, with additional analyses on the 10th and 90th percentiles. Results

SUBMITTER: Gheorghe DA 

PROVIDER: S-EPMC12534549 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature