Visceral adipose tissue and hepatic fat as determinants of carotid atherosclerosis.

ABSTRACT:

Background

Visceral adipose tissue (VAT) and hepatic fat (HF) contribute to multiple health risks, including diabetes, hypertension, cardiovascular disease, cognitive decline, and cancer. The objective of this study is to determine whether VAT and HF are associated with carotid atherosclerosis beyond traditional cardiovascular risk factors.

Methods

Participants in the Canadian Alliance of Healthy Hearts and Minds (CAHHM) cohort study (n = 6760; average age= 57.1; 54.9% female) underwent MRI for VAT volume, hepatic fat fraction (HFF), and carotid atherosclerosis assessed by carotid wall volume (CWV). Regression models were used to assess the associations of VAT and HF with carotid atherosclerosis, separately in males and females, controlling for other cardiovascular risk fact

SUBMITTER: de Souza RJ 

PROVIDER: S-EPMC12534607 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature