Early Outcome Analysis of Intravitreal Aflibercept 8 mg Treatment in Naive Patients with Neovascular Age-Related Macular Degeneration Using Artificial Intelligence.

ABSTRACT:

Introduction

Neovascular age-related macular degeneration (nAMD) is one of the leading causes of vision loss, often requiring frequent injections. Our aim is to report the early outcomes of intravitreal aflibercept (IVA) 8 mg treatment in naïve patients with nAMD.

Methods

An observational, retrospective, monocentric study was conducted at Swiss Visio Montchoisi, Lausanne, Switzerland. A total of 51 eyes of 48 patients with naïve macular neovascularization (MNV) secondary to AMD received a loading phase of three-monthly IVA followed by a monthly observational phase until fluid recurrence. At each visit, all patients had a full ophthalmological exam, including spectral-domain optical coherence tomography (SD-OCT), which was analysed manually and with artificial intelligence (A

SUBMITTER: Bartolomeo N 

PROVIDER: S-EPMC12534677 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature