The role of medication regimen complexity in diabetes management: a rapid review.

ABSTRACT: Combination therapy is commonly used to achieve better glycemic control, but Medication Regimen Complexity (MRC) can pose challenges for treatment adherence and outcomes. While some studies have explored the impact of MRC on patient outcomes, evidence remains inconclusive. Therefore, we aimed to explore the impact of MRC on diabetes management. This rapid review systematically identified studies on diabetes patients with complex medication regimens and their clinical and nonclinical outcomes. A comprehensive search was conducted across four databases (PubMed, Web of Science, Scopus, and Cochrane) from January 1967 to September 2023. Study quality was assessed using the Joanna Briggs Institute tool, while the overall evidence certainty was evaluated using the GRADE approach. Thirteen studie

SUBMITTER: Khayyat SM 

PROVIDER: S-EPMC12534806 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature