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Clinical and histological characterization of 19 chondro-osseous respiratory epithelial adenomatoid hamartomas and 2 respiratory epithelial adenomatoid hamartomas in dogs.


ABSTRACT: Nasal biopsies from 21 dogs diagnosed with chondro-osseous respiratory epithelial adenomatoid hamartomas or respiratory epithelial adenomatoid hamartomas were reviewed. Associated lesions included angiomatous tissue (4/21), seromucinous gland proliferation (2/21), and polyps (3/21), and all had chronic inflammation. Dogs had epistaxis (14/21), sneezing (9/21), decreased airflow (8/21), congestion (6/21), and discharge (5/21). In addition to a mass lesion, computed tomography findings (n = 19) included turbinate lysis (10/19), cribriform plate and orbit erosion (4/19), and contralateral extension (8/19). In 16 dogs with outcome data collected 0-49 months after diagnosis, 13 had continued respiratory symptoms, 11 of which received medical management; 2 of the 3 dogs with improvement h

SUBMITTER: Forster A 

PROVIDER: S-EPMC12534865 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature