Smoking-Attributable Age-Related Macular Degeneration Vision Loss in China: 1990-2021 Trends and 2040 Projections.

ABSTRACT:

Purpose

This study aimed to analyze the spatiotemporal burden of vision loss due to age-related macular degeneration (AMD) attributable to smoking in China from 1990 to 2021, projecting to 2040.

Methods

Based on the Global Burden of Diseases 2021 dataset, we quantified epidemiological metrics for AMD-related vision loss. Joinpoint regression identified trend turning points in the smoking-attributable AMD vision loss burden. The Autoregressive Integrated Moving Average model projected trajectories to 2040. Pearson correlation assessed associations between the Socio-demographic Index and burden indicators.

Results

From 1990 to 2021, AMD-related vision loss cases surged approximately 200% (2021: 2,647,261 [95% uncertainty interval {UI}: 2,185,651-3,258,896]), whereas Yea

SUBMITTER: Huang L 

PROVIDER: S-EPMC12534889 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature