MiR-4793-3p predicts poor prognosis and regulates ferroptosis and invasiveness of breast cancer via targeting RNF169.

ABSTRACT:

Background

The prognosis prediction of breast cancer is a challenging problem in the clinic. Identifying reliable biomarkers and revealing the regulatory mechanism underlying the progression of breast cancer cells would benefit the treatment and outcomes of breast cancer patients.

Objectives

This study aims to explore a novel biomarker related with tumor progression and clinical prognosis, focusing on miR-4793-3p and its targets.

Materials and methods

The study enrolled 133 patients with breast cancer, and tissue samples were obtained. Expression of miR-4793-3p and its clinical significance were evaluated from the perspective of molecular subtypes, disease development, and prognosis. The regulatory effect and mechanism of miR-4793-3p in the biological function of brea

SUBMITTER: Chang Y 

PROVIDER: S-EPMC12534942 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature