Understanding sex-related differences among Asian axial spondyloarthritis patients: a systematic review and meta-analysis : Sex differences and clinical outcomes in Asian axial spondyloarthritis.

ABSTRACT:

Background

Axial spondyloarthritis (axSpA) exhibits notable sex-related differences, particularly in Asian populations, influenced by genetic, cultural, and healthcare factors. This systematic review and meta-analysis assess sex-specific disparities in axSpA among Asian patients.

Methods

A systematic search in PubMed, Embase, and Google Scholar (up to January 30, 2025) included studies reporting sex-specific differences in clinical presentation, diagnostic delay, treatment response, and quality of life. The study included 31,523 males and 10,815 females. Risk of bias was assessed using the ROBINS-I tool. Meta-analysis was performed using R and Jamovi, with heterogeneity assessed via I² statistics.

Results

Thirty studies comprising 31,523 male and 10,815 fem

SUBMITTER: Paudel P 

PROVIDER: S-EPMC12535000 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature