Nasopharyngeal carcinoma in sub-Saharan Africa: clinicopathological profiles, patterns of care, and survival outcomes of patients treated at a leading radiotherapy center.

ABSTRACT:

Introduction

In sub-Saharan Africa, the clinicopathological features, management strategies, and survival outcomes of nasopharyngeal carcinoma (NPC) remain underreported, posing challenges to improving patient care and treatment outcomes. The aim of the study was to evaluate the clinicopathological profiles, patterns of care, and survival of patients with NPC treated with curative intent at a major radiotherapy center in sub-Saharan Africa.

Methods

This retrospective cohort study analyzed 83 patients with histopathologically confirmed NPC treated over a 10-year period. Data on demographics, clinical features, management, and treatment outcomes were extracted from patients' medical records. Statistical analyses were conducted using SPSS, with a significance threshold of p < 0

SUBMITTER: Kyei KA 

PROVIDER: S-EPMC12535049 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature