Vaping versus smoking: a quest for long-term impact in a mouse model.

ABSTRACT: Smokers consider that electronic cigarettes are safer than tobacco and are marketed as safe products. Nevertheless, reports show the exposure to high levels of electronic cigarette aerosols (ECA) activates lung cells and triggers inflammation and structural alterations after chronic exposure. In order to assess the potential harmful long term effect of exposure to ECA, we investigated in mice, its effect on lung and systemic inflammation as well as on lung function. To reproduce closely the situation frequently encountered in human, we exposed mice during 1 h/day during 3 or 6 months with two levels of electronic cigarette power in comparison with mice exposed to cigarette smoke (CS). Lung and systemic inflammation was evaluated by measuring cell recruitment and activation or cytokine conc

SUBMITTER: Massara L 

PROVIDER: S-EPMC12535149 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature