Mitochondrial Introgression With Potential Functional Effects in North American Yak.

ABSTRACT: The domestic yak (Bos grunniens) has experienced introgression with domestic cattle in its native Qinghai-Tibetan Plateau and after introduction to North America (NA), although the extent to which the latter has occurred is not well documented. We used complete mitochondrial (mtDNA) sequences of 12 NA yak and aligned them to the B. taurus reference genome for annotation. Identified variation among the NA haplotypes included a total of 982 variants, of which 99 were nonsynonymous single nucleotide polymorphisms. Among the NA yak, we identified nine unique mitotypes, which a haplotype network separated into two distinct clusters. A maximum likelihood tree including 86 Bovidae taxa revealed six NA yak haplotypes formed a clade with B. indicus; the other three haplotypes g

SUBMITTER: Treffer LK 

PROVIDER: S-EPMC12535201 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature