Antifungal Resistance and Synergistic Therapy in Candida Spp. Isolated From Bottlenose Dolphins Under Human Care: Implications for One Health Management.

ABSTRACT:

Introduction

Routine antifungal susceptibility testing in animals is uncommon, yet increasingly relevant as antifungal resistance rises among marine mammals under human care. Despite the critical health risks posed by fungal infections, little research addresses multidrug-resistant Candida spp. in marine mammals under human care. This study aims to investigate the prevalence and antifungal susceptibility profiles of Candida species isolated from faecal and blowhole samples of bottlenose dolphins (Tursiops truncatus) under human care and to evaluate the in vitro efficacy of antifungal combination therapies within a One Health framework that considers environmental reservoirs and potential zoonotic risks.

Methods

Candida species were isolated from 14 faecal and 9 blowhole exha

SUBMITTER: Biancani B 

PROVIDER: S-EPMC12535303 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature