Oxidative Addition of Aryl Bromides at Palladium(I) to form Palladium(III) Complexes.

ABSTRACT: Herein, we report the first systematic study of the oxidative addition of aryl bromides to a Pd^I center to generate organometallic Pd^III complexes. These isolable Pd^III complexes stabilized by tetradentate macrocyclic pyridinophane ligands exhibit distinct UV-vis and EPR spectroscopic signatures that allowed for the monitoring of their generation in situ. These ligand scaffolds were sterically and electronically tuned using a modular synthetic approach to probe the kinetic properties and activation parameters of the oxidative addition reaction, and a combination of UV-vis and cryo stopped-flow spectroscopic studies reveal a rapid oxidative addition step occurring at a Pd^I center. In addition, these results are in strong agreement with our recent

SUBMITTER: Bouley BS 

PROVIDER: S-EPMC12535386 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature