Aphasia-specific or generic outcomes? a comparison of two health-related quality of life instruments for economic evaluations of aphasia treatments.

ABSTRACT:

Purpose

Economic evaluations based on health-related quality of life (HRQOL) inform healthcare decisions. The generic EuroQol 5-Dimensions Health Questionnaire, 3-Level (EQ-5D-3L) permits conversion to utility values required for economic evaluations but is not validated for people with aphasia. The aphasia-specific Stroke and Aphasia Quality of Life Scale-39 g (SAQOL-39g) measures HRQOL, however, cannot be used to generate utility values. This study aimed to compare the performance of these two instruments.

Methods

HRQOL was rated at baseline and 12 weeks in participants of the Constraint Induced or Multi-Modal Personalised Aphasia Rehabilitation (COMPARE) randomised controlled trial. We assessed: (1) distribution of self-rated HRQOL scores, (2) convergent validity between

SUBMITTER: Zingelman S 

PROVIDER: S-EPMC12535536 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature