Management and prognosis of ultra high-risk gestational trophoblastic neoplasia patients: a long-term retrospective study.

ABSTRACT:

Background

The prognosis for patients with ultra high-risk gestational trophoblastic neoplasia (GTN) is significantly worse, and there is currently no consensus regarding the optimal treatment strategies for this specific patient population.

Objectives

This study aims to investigate the clinical characteristics, treatment responses, outcomes, and prognostic risk factors in ultra high-risk GTN patients with an International Federation of Gynecology and Obstetrics (FIGO) score of 13 or higher.

Design

Retrospective study.

Methods

Medical records of 36 GTN patients with FIGO score ⩾ 13, treated at the first affiliated hospital of Zhengzhou University, China, from January 2015 to June 2024, were retrospectively reviewed. Chi-square tests, univariate analysis, and Ka

SUBMITTER: Mao M 

PROVIDER: S-EPMC12535631 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature