The Effect of Oral Probiotic <i>Bacillus amyloliquefaciens</i> on Intestinal Microbiota, Intestinal Structure, Serum Antioxidant Capacity and Inflammatory Responses of Heat Stressed Rats.

ABSTRACT: This study investigated the effect of Bacillus amyloliquefaciens (BaSC06) in alleviating heat stress in rats. The rats were randomly divided into four groups. Each rat in Group 1 and Group 3 received oral 1 ml/day of PBS, whereas those in Group 2 and Group 4 were administered 1 ml/day of BaSC06 (10⁸ CFU/ml). After two weeks, the rats in Groups 3 and 4 were exposed to heat stress at 42°C for 30 min, while those in Groups 1 and 2 were maintained at 25°C. The result showed that oral BaSC06 increased abundance of Firmicutes phylum and Ruminococcaceae Family along with reduced level of Bacteroidetes family. Compared to Group 1, the height of small intestine villi increased significantly (P < 0.05) in Group 2, and intestinal villus heig

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12535860 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature