Insights into mucosal and systemic immune responses of African catfish, Clarias gariepinus, to chilodonellosis: A natural infection study.

ABSTRACT: A natural parasitic infection with the external ciliate protozoan, Chilodonella hexasticha, was recorded 3 days post-transportation (PT) in the gills and skin of African catfish (Clarias gariepinus). Infected fish displayed behavioural changes and typical signs of infection. Mortalities started on day 7 PT and stopped on day 13 PT, where cumulative mortality reached 62.2%. The expression of immune-relevant genes, interleukin-1β (IL-1β), major histocompatibility complex class II (MHC-II) and interleukin-10 (IL-10) in the gills, head kidneys and spleen of the Chilodonella-infected and control uninfected fish were investigated using quantitative real-time polymerase chain reaction (PCR) on days 7-, 14- and 28 PT. Expression levels of IL-1β in the gills showed a significant upregulation on day

SUBMITTER: Emeish WFA 

PROVIDER: S-EPMC12536051 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature