Utility of admission biomarkers in predicting severe outcomes and triage in acute febrile illness: A cohort study.

ABSTRACT: ObjectivesTo determine the role of biomarkers in acute febrile illness patients at admission in predicting moderate-to-severe multiorgan dysfunction at 24 h of hospitalization and the need for invasive mechanical ventilation at 48 h of hospitalization.MethodsThis prospective cohort study was conducted among 100 acute febrile illness patients brought to the emergency department. Biochemical and clinical parameters at hospital admission were recorded. The highest Sequential Organ Failure Assessment score was calculated at 24 h of hospitalization. The need for invasive mechanical ventilation at 48 h of hospitalization was evaluated.ResultsOf the 95 acute febrile illness patients, 60 (63.15%) had moderate-to-severe multiorgan dysfunction. Multivariable logistic regression showed that admission

SUBMITTER: Srinivas T 

PROVIDER: S-EPMC12536115 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature