Valorization of <i>Channa striatus</i> waste skin for developing marine collagen peptide based hydrogels for potential wound dressings.

ABSTRACT: This study focuses on the extraction and characterization of a bioactive collagen peptide from waste skin of a local species of fish, the Channa striatus/snakehead/'shol' fish. The extracted peptides were characterized and optimized for the formulation of chitosan/PVA/collagen peptide (CP) hydrogel which has not been done previously. The facile extraction process involved using alkali, butanol, and protease for non-collagenous protein and fat removal, and enzymatic hydrolysis respectively. Hydrogels were formulated using a non-toxic freeze-thaw technique with multiple combinations of chitosan, PVA, and collagen peptide and characterized with SEM, FTIR, swelling ratio, gel content, porosity, evaporation rate, and antibacterial and anti-inflammatory activity. The FTIR fingerprint of t

SUBMITTER: Tarannum T 

PROVIDER: S-EPMC12536424 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature