Association between DDT or its byproducts and T2DM: a systematic review and meta-analysis.

ABSTRACT:

Background

Currently, type 2 diabetes mellitus (T2DM) is among the fastest-growing global health emergencies of the century. Emerging evidence from epidemiological studies suggests a potential positive association between exposure to dichlorodiphenyltrichloroethane (DDT) or its byproducts and an increasing risk of T2DM.

Objective

We conducted a systematic review and meta-analysis to quantify the association between DDT or its byproducts and T2DM. Additionally, we aimed to identify the sources of heterogeneity contributing to the inconsistency of the results.

Methods

Data analysis: assess the quality of the included studies using the Risk Of Bias In Non-randomized Studies of Exposure tool, determine the source of heterogeneity using subgroup analysis, sensitivity analy

SUBMITTER: Tian W 

PROVIDER: S-EPMC12536502 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature