Genome-wide profiling and functional study of short N-terminal H2B variants in Arabidopsis.

ABSTRACT:

Introduction

Nucleosomes harboring specific histone variants show distinct chromatin localization patterns and regulatory functions, thereby playing crucial roles in epigenetic regulation. Compared to the well-understood variants of H2A and H3, the study about H2B variants is emerging. Deciphering the roles and regulatory mechanisms of H2B variants in plants will provide more knowledges about epigenetic regulations in plant biology.

Objectives

Using the model plant Arabidopsis thaliana as the research subject, we systematically analyzed histone H2B variants, four short N-terminal histone H2B variants (snH2Bs) were identified. The genomic distribution characteristics of these snH2Bs, their impact on plant growth, and the potential regulatory mechanisms were studied.

Method

SUBMITTER: Yao P 

PROVIDER: S-EPMC12536603 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature