Arsenic in Drinking Water and Prostate Cancer: A Population-Based Case-Control Study in Northern Chile.

ABSTRACT:

Background

Epidemiologic evidence demonstrates increased lung, bladder, and skin cancer risk among individuals exposed to arsenic in drinking water. Some studies report associations with prostate cancer, but data are limited. This study aimed to examine the association between arsenic in drinking water and prostate cancer in Northern Chile. With its wide range of exposure (<10-860 µg/L), large population, and accurate information on historic exposures, Northern Chile is the best place to investigate the human carcinogenic effects of arsenic.

Methods

A case-control study conducted from 2015 to 2019 enrolled 343 prostate cancer cases and 337 age-matched controls among men ages ≥40 years. Cases were ascertained from cancer committees, hospitals, and medical facilities in the ar

SUBMITTER: Schwalb ME 

PROVIDER: S-EPMC12536798 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature