Uric acid electrochemical biosensor based on a laser-induced graphene electrode modified with a Honey-mediated nanocomposite of reduced graphene oxide and bimetallic silver-cobalt.

ABSTRACT: Abnormal uric acid (UA) levels are commonly linked to several metabolomic or internal organ problems. Electrochemical-based tests have been used as alternative early screening methods to determine the levels of biomarkers, including UA. Electrochemical biosensors based on laser-induced graphene (LIG) electrodes could offer a promising alternative to realize a low-cost biosensor for biomarker detection. In this study, an LIG electrode was modified with a nanocomposite composed of reduced graphene oxide and silver-cobalt bimetal (rGO/AgCo), resulting in its enhanced sensitivity and selectivity for the detection of UA. Furthermore, to promote eco-friendliness, honey was utilized as the mediator to reduce and stabilize the nanoparticles during the creation of the nanocomposite. Differential pu

SUBMITTER: Anshori I 

PROVIDER: S-EPMC12536868 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature